Nutritional Supplement in Hair Loss

Androgenetic Alopecia (AGA) is the most common form of hair loss

The main type of hair loss in both sexes is male or female pattern hair loss (known as androgenetic alopecia) caused by an imbalance in the sex hormones or androgens in the body, sometimes associated with a hereditary or genetic predisposition to this condition

• AGA is caused by a progressive reduction in the diameter, length and pigmentation of the hair.
• Male-Pattern Hair Loss (MPHL), the hair loss typically presents itself as either a receding front hairline, loss of hair on the crown (vertex) of the scalp, or a combination of both.
• Female-pattern hair loss (FPHL) typically presents as a diffuse thinning of the hair across the entire scalp.

  • Ideal oral supplement in Androgenetic Alopecia (AGA)
  • It should help in Hair Recovery & Regrowth as a Nutritional Supplement
  • It should combine key Anti-oxidants, Anti-lnflammatory Agents & Botanical 5-a Reductase lnhibitors

Benefits of an oral supplement in Androgenetic Alopecia

It should help to restore and support thicker and faster growth of thinning hair through five key pathways:

  1. Supporting stimulation of hair growth
  2. Helping support in prevention of hair loss
  3. Nutritional support to help block DHT
  4. Delivering key antioxidants
  5. Supplying anti-inflammatory benefits

Ideal Ingredients of a hair growth supplement

Beta Sitosterol

  • Studies have shown plant phytosterols such as Beta-Sitosterol nourish and support a healthy and normal androgen sex hormone state in the body
  • They also nourish and support a more normal and healthy state of reduced inflammation

Omega 3 & 6 Fatty acids

  • Omega fatty acids are a key family of polyunsaturated fats. These are essential fats, obtained from dietary sources as body cannot synthesis in sufficient quantity
  • They help nourish and support a more normal and healthy state of reduced inflammation.
  • Inflammation is commonly associated with hair loss and other scalp disorders

Soy Isoflavones

  • Studies have shown Soy lsoflavones nourish and support a healthy and more normally balanced androgen sex hormone state in the body.
  • They provide potent antioxidant protection to help prevent oxidative stress-induced aging of the hair follicle

Melatonin

  • Melatonin is important in hair health. The anagen hair follicle (HF) produces melatonin internally.
  • Melatonin is a potent antioxidant-free radical scavenger with a capacity to help protect the follicle from effects of systemic stress.
  • Melatonin also helps nourish and support a healthy and normal androgen sex hormone state in the body.

Green Tea Extracts

  • Green Tea provides potent antioxidant protection to help prevent oxidative stress-induced aging of the hair follicle
  • It helps to reduced inflammation & balance the androgen level in body
  • Epigallocatechin-3-gallate, the main polyphenol in green tea, helps protect and stimulate the hair follicle and studies have shown it helps nourish and prolong the anagen growth phase.

Vitamin D

  •  Vitamin D pathway has been shown to regulate hair follicle biology in mammals and humans and is crucial for hair health.
  • Vitamin D deficiency is associated with increased hair shedding

REFERENECE: Nichols, Anna & Hughes, Olivia & Canazza, Agnese & Zaiac, Martin. (2017). An Open-Label Evaluator Blinded Study of the Efficacy and Safety of a New Nutritional Supplement in Androgenetic Alopecia: A Pilot Study. Journal of Clinical and Aesthetic Dermatology. 10. 52-56.

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MINOXIDIL FOR HAIR LOSS

Hair loss Treatment

Minoxidil is an FDA-approved medication commonly used for the treatment of androgenetic alopecia, which is a type of hair loss that is primarily caused by genetics and hormonal factors. Minoxidil is available as a topical solution or foam and is applied directly to the scalp.

Minoxidil works by promoting hair growth and preventing further hair loss. It is thought to increase the blood flow to the hair follicles and stimulate the hair growth cycle. However, the exact mechanism of how minoxidil works is not fully understood.

When using minoxidil for androgenetic alopecia, it’s important to note the following:

1. Results may vary: Minoxidil has been shown to be effective in promoting hair regrowth in some individuals, but the results can vary from person to person. Some individuals may experience significant regrowth, while others may see more modest results or no improvement at all.

2. Consistency is key: Minoxidil should be used regularly and as directed for optimal results. It is typically applied twice daily to the affected areas of the scalp. It’s important to follow the instructions provided by your healthcare provider or the product label.

3. Patience is required: Hair regrowth takes time, and it may take several months of consistent use before you start noticing any significant changes. It’s important to be patient and continue using minoxidil as recommended, even if you don’t see immediate results.

4. Maintenance is necessary: Minoxidil is not a cure for androgenetic alopecia. If you stop using minoxidil, any hair regrowth that occurred may be lost, and hair loss may resume. Therefore, it is usually recommended to continue using minoxidil to maintain the results.

5. Potential side effects: Minoxidil is generally considered safe for most people when used as directed. However, some individuals may experience side effects such as scalp irritation, itching, dryness, or unwanted hair growth on other parts of the body. If you experience any concerning side effects, it’s best to consult with your healthcare provider.

It’s important to consult with a healthcare professional, such as a dermatologist or a hair loss specialist, before starting minoxidil or any other treatment for androgenetic alopecia. They can evaluate your specific situation, provide a diagnosis, and recommend the most appropriate treatment options for you.

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Unveiling Nature’s Potential: Natural Inhibitors of Dihydrotestosterone for Hair Loss

Introduction: In androgenetic alopecia, dihydrotestosterone (DHT) plays a significant role. It is an important hormone for the development of male characteristics, increased sensitivity to DHT can lead to various health concerns, such as hair loss, acne, and an enlarged prostate. While there are pharmaceutical interventions available, exploring the realm of natural inhibitors of DHT can offer a promising alternative. In this blog, we’ll delve into some remarkable natural substances that have shown potential in inhibiting DHT production and minimizing its effects.

Saw Palmetto: Derived from the berries of the Serenoa repens plant, saw palmetto has long been recognized for its ability to inhibit the enzyme 5-alpha-reductase, which converts testosterone into DHT. By inhibiting this enzyme, saw palmetto helps reduce the levels of DHT in the body. It has gained popularity as a natural remedy for androgenetic alopecia (pattern hair loss).

Pumpkin Seed Oil: Pumpkin seed oil is another natural inhibitor of DHT, rich in antioxidants, minerals, and essential fatty acids. It contains high levels of phytosterols, particularly beta-sitosterol, which helps block the conversion of testosterone to DHT. Incorporating pumpkin seed oil into your diet or using it as a supplement may aid reducing hair loss.

Green Tea: Renowned for its numerous health benefits, green tea contains compounds called catechins. Epigallocatechin gallate (EGCG), a potent catechin found in green tea, has been shown to inhibit 5-alpha-reductase, thereby reducing DHT levels. By including green tea in your daily routine, you not only enjoy its refreshing taste but also harness its potential DHT-inhibiting effects.

Zinc is an essential mineral that plays a vital role in hormonal balance. It is involved in the metabolism of testosterone and has been found to inhibit the enzyme responsible for the conversion of testosterone to DHT. Consuming zinc-rich foods like oysters, nuts, seeds, and legumes, or using zinc supplements, may help regulate DHT production.

Pygeum Africanum: Derived from the bark of the African cherry tree, Pygeum africanum contains phytosterols, pentacyclic triterpenes, and other bioactive compounds that inhibit 5-alpha-reductase activity, consequently reducing DHT levels. Incorporating Pygeum africanum supplements into your routine may contribute to maintaining a healthy balance of DHT.

Stinging Nettle: Stinging nettle root extract has gained attention for its potential to inhibit the conversion of testosterone to DHT. It contains compounds that bind to the enzymes involved in this conversion, effectively reducing DHT production. While more research is needed, stinging nettle supplements have shown promise in managing conditions influenced by DHT, such hair loss.

Conclusion: Balancing DHT levels naturally can be a multifaceted approach that involves lifestyle modifications, dietary changes, and incorporating natural inhibitors into your routine. While these natural inhibitors have shown promise in reducing DHT production, it’s important to consult with a healthcare professional before making any significant changes to your regimen, especially if you have pre-existing conditions or are taking medications.

Remember, achieving hormonal balance is a holistic process that involves overall well-being. Embrace a healthy lifestyle, engage in regular exercise, manage stress levels, and nourish your body with a balanced diet. By doing so, you can optimize your hormone levels and promote long-term health.

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COVID-19 AND HAIR LOSS?

In coronavirus pandemic, expect the unexpected.

Temporary hair loss is normal after a fever or illness

Fever is a symptom of COVID-19. Few months after high fever or recovery from an illness, many people notice hair loss. It’s not hair loss, it’s actually hair shedding telogen effluvium . It happens when more than normal hairs enter the shedding (telogen) phase of the hair cycle at the same time. A fever or illness can force hairs into the shedding phase.

People notice hair shedding 2-3 months after a fever or illness. Handfuls of hair come out while showering or brushing hair.  Hair shedding can last 6-9 months before it stops. Hairs start to look normal again and shedding stops.

Telogen effluvium can cause noticeable hair shedding. In case of a rash, itchy scalp, or burning, see a dermatologist.

Stress can cause temporary hair shedding

Even if you didn’t have a fever or COVID-19, you may get hair shedding. Emotional stress can cause more hairs than normal to enter the shedding phase. Everyone is feeling more stressed and anxious during the pandemic. Hair shedding begins 2-3 months after the stress. Hair falling out in clumps can add to the stress. De-stressing will stop the excessive hair shedding.

Hair shedding due to a fever, illness, or stress, tends to normalize on its own. Most will get normal hair fullness within 6-9 months.

If something other than telogen effluvium is causing hair-loss, a dermatologist can help confirm the diagnosis.

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Treatment Options for Male Pattern Hair Loss (Androgenetic Alopecia)

Male Pattern Hair Loss

Medical treatment

Minoxidil:  5% minoxidil liquid or foam application to the scalp helps to slow down the progression of hair loss and may partially restore hair. Minoxidil liquid or foam is applied on the affected scalp (not the hair) using a pump spray or dropper device. It is spread evenly over the hair loss affected area lightly and does not need to be massaged in. Minoxidil can cause skin dryness, redness, itching and/or scaling at the site of application and should not be applied on cuts or open wounds. It should be used for at least 6 months before any benefit may be noticed. Any response obtained is only maintained for as long as the treatment is continued. Minoxidil may cause hairs to fall initially during the first 2-8 weeks of treatment, and usually this subsides when new hairs start to grow.

Finasteride: Finasteride tablets reduce levels of dihydrotestosterone (DHT) hormone, slows down hair loss and helps in regrowth of hair. Continuous use for 3 – 6 months is required before a benefit can be usually seen. Decreased libido and erectile dysfunction are recognized side-effects of this treatment. Beneficial effects on hair growth are lost within 6 to 12 months of discontinuing treatment.

All topical and oral treatments work only till the time treatment is continued.

Camouflage treatment

Wigs and hair pieces:

Wigs, toupees, and hair extensions are helpful in disguising hair loss. There are two types of hairpiece; synthetic or made from real hair.

Synthetic wigs and hairpieces usually last about 6 -9 months, are easy to wash and maintain, but may be susceptible to heat damage and are hot to wear.

Real hair wigs or hairpieces look more natural, can be styled easily and are cooler to wear.

Skin camouflage:

Spray preparations containing small, pigmented fibers help to disguise hair loss affected area. These preparations wash away if the hair gets wet, and only tend to last between shampooing.

Surgical treatments:

Surgical treatment includes.

  • hair transplantation, a procedure where hair follicles are taken from the sides and back of the scalp and transplanted onto the bald areas; and
  • scalp reduction, where a section of bald area is excised, and the hair-bearing scalp is stretched to cover the gap. Tissue expanders are used to stretch the skin.
  • Platelet rich Plasma Therapy: PRP is a safe and effective hair loss treatment. The procedure involves blood centrifugation that separates red blood cells from plasma. Plasma rich in platelets containing growth factors is injected into the patient’s hair follicles. Injections are given once a month for the first three months, and then once every three to six months thereafter. Patients may notice less loss of hair after therapy. PRP therapy has high success and satisfaction rates in patients with hereditary hair baldness or thinning. PRP may be used as an adjuvant with other medical treatments to give patients the best possible results.

 Self-care?

Protect bald areas of your scalp from sun to prevent sunburn and to reduce the chances of developing long-term sun damage.

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